Almost one third of all new thyroid cancers diagnosed are in young adults ages 20 to 40 and thyroid carcinomas represent approximately 6-12% of all malignancies diagnosed in this age group. Thyroid carcinomas are 5 times more common in females than males among 20 to 40 year olds, accounting for 4% of all cancers in women. Thyroid cancer is also one of the most common malignancies to occur during pregnancy and therefore it is imperative to assess the treatment and management of such cases individually with possible delay in surgery and radioactive iodine therapy. Overall survival rates are exceptional with 5-year survival rates for individuals diagnosed before the age of 40 above 99%. Future research will hopefully shed light to understanding the long-term and potentially adverse effects of different thyroid treatment therapies as well as their effects on reproduction, which may impact the survivorship of this community.
Source: Ying A, Huh W, Bottomley S, et al. Thyroid Cancer in Young Adults. Semin Oncol. 2009; 36:258-274.
An analysis of discrepancies between United Kingdom cancer research funding and societal burden and a comparison to previous and United States values.
Health Res Policy Syst. 2015;13(1):62
Authors: Carter AJ, Delarosa B...
Increased risk of second malignant neoplasms in adolescents and young adults with cancer.
Cancer. 2015 Oct 6;
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BACKGROUND: The authors describe the...
Coincidence between malignant perivascular epithelioid cell tumor arising in the gastric serosa and lung adenocarcinoma.
World J Gastroenterol. 2015 Jan 28;21(4):1349-56
Authors: Yamada S, Nabeshima A, Noguchi H, Nawata...
Socio-demographic disparities in differentiated thyroid cancer survival among adolescents and young adults in California.
Thyroid. 2015 Mar 17;
Authors: Keegan T, Grogan R, Parsons H, Tao L, White MG, Onel K, Horn-Ross PL
BACKGROUND: Few studies have focused on prognostic factors among adolescents and young adults (AYAs...
Survivorship in adolescents and young adults.
Acta Haematol. 2014;132(3-4):383-90
Authors: Kishtagari A, Tavakkoli M, Park JH
In the USA, approximately 26,000 adolescents and young adults (AYAs) aged 15-29 years are diagnosed with cancer every year. The cure rate...
Long-term survival and conditional survival of cancer patients in Japan using population-based cancer registry data.
Cancer Sci. 2014 Sep 2;
Authors: Ito Y, Miyashiro I, Ito H, Hosono S, Chihara D, Nakata-Yamada K, Nakayama M, Matsuzaka M, Hattori M, Sugiyama H, Oze I, Tanaka R, Nomura E, Nishino Y, Matsuda...
Cancer Incidence and Survival among Adolescents and Young Adults in Korea.
PLoS One. 2014;9(5):e96088
Authors: Moon EK, Park HJ, Oh CM, Jung KW, Shin HY, Park BK, Won YJ
BACKGROUND: In Korea, cancer is the third leading cause of death among adolescents and...
Comparison of secondary and primary thyroid cancer in adolescents and young adults.
Cancer. 2014 Apr 15;120(8):1155-1161
Authors: Goldfarb M, Freyer DR
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Unmet information and support needs in newly diagnosed thyroid cancer: comparison of adolescents/young adults (AYA) and older patients.
J Cancer Surviv. 2014 Feb 26;
Authors: Goldfarb M, Casillas J
PURPOSE: Thyroid cancer (TC) is the most common cancer in...
Insurance status and distant-stage disease at diagnosis among adolescent and young adult patients with cancer aged 15 to 39 years: National Cancer Data Base, 2004 through 2010.
Cancer. 2014 Jan 28;
Authors: Robbins AS, Lerro CC, Barr RD
BACKGROUND: The percentage of...
Comparison of Radioiodine Utilization in Adolescent and Young Adult (AYA) and Older Thyroid Cancers Patients.
Endocr Pract. 2013 Dec 10;:1-20
Authors: Goldfarb M, Sener SF
Objective: Differentiated thyroid cancer (DTC) is one of the most common cancers in adolescents and young adults (AYA: aged 15-39). Although most AYAs...
Cancer in adolescents and young adults in countries with limited resources.
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Cancer in adolescents and young adults (AYA) represents a higher fraction of all cancer in countries that are still...
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