Almost one third of all new thyroid cancers diagnosed are in young adults ages 20 to 40 and thyroid carcinomas represent approximately 6-12% of all malignancies diagnosed in this age group. Thyroid carcinomas are 5 times more common in females than males among 20 to 40 year olds, accounting for 4% of all cancers in women. Thyroid cancer is also one of the most common malignancies to occur during pregnancy and therefore it is imperative to assess the treatment and management of such cases individually with possible delay in surgery and radioactive iodine therapy. Overall survival rates are exceptional with 5-year survival rates for individuals diagnosed before the age of 40 above 99%. Future research will hopefully shed light to understanding the long-term and potentially adverse effects of different thyroid treatment therapies as well as their effects on reproduction, which may impact the survivorship of this community.
Source: Ying A, Huh W, Bottomley S, et al. Thyroid Cancer in Young Adults. Semin Oncol. 2009; 36:258-274.
Age at Primary Malignancy Determines Survival in Adolescent and Young Adults That Develop a Secondary Thyroid Cancer.
J Adolesc Young Adult Oncol. 2016 Apr 4;
Authors: Lau BJ, Goldfarb M
PURPOSE: Second malignancy status is a risk factor for death in adolescent and young adults (AYAs) (ages 15-39) with thyroid cancer (TC...
Comparison of cancer survival trends in the United States of adolescents and young adults with those in children and older adults.
Cancer. 2016 Feb 5;
Authors: Keegan TH, Ries LA, Barr RD, Geiger AM, Dahlke DV, Pollock BH, Bleyer A, National Cancer...
Incidence and incidence trends of the most frequent cancers in adolescent and young adult Americans, including "nonmalignant/noninvasive" tumors.
Cancer. 2016 Feb 5;
Authors: Barr RD, Ries LA, Lewis DR, Harlan LC, Keegan TH, Pollock BH, Bleyer WA, US...
An analysis of discrepancies between United Kingdom cancer research funding and societal burden and a comparison to previous and United States values.
Health Res Policy Syst. 2015;13:62
Increased risk of second malignant neoplasms in adolescents and young adults with cancer.
Cancer. 2015 Oct 6;
Authors: Lee JS, DuBois SG, Coccia PF, Bleyer A, Olin RL, Goldsby RE
BACKGROUND: The authors describe the...
Coincidence between malignant perivascular epithelioid cell tumor arising in the gastric serosa and lung adenocarcinoma.
World J Gastroenterol. 2015 Jan 28;21(4):1349-56
Authors: Yamada S, Nabeshima A, Noguchi H, Nawata...
Socio-demographic disparities in differentiated thyroid cancer survival among adolescents and young adults in California.
Thyroid. 2015 Mar 17;
Authors: Keegan T, Grogan R, Parsons H, Tao L, White MG, Onel K, Horn-Ross PL
BACKGROUND: Few studies have focused on prognostic factors among adolescents and young adults (AYAs...
Survivorship in adolescents and young adults.
Acta Haematol. 2014;132(3-4):383-90
Authors: Kishtagari A, Tavakkoli M, Park JH
In the USA, approximately 26,000 adolescents and young adults (AYAs) aged 15-29 years are diagnosed with cancer every year. The cure rate...
Long-term survival and conditional survival of cancer patients in Japan using population-based cancer registry data.
Cancer Sci. 2014 Sep 2;
Authors: Ito Y, Miyashiro I, Ito H, Hosono S, Chihara D, Nakata-Yamada K, Nakayama M, Matsuzaka M, Hattori M, Sugiyama H, Oze I, Tanaka R, Nomura E, Nishino Y, Matsuda...
Cancer Incidence and Survival among Adolescents and Young Adults in Korea.
PLoS One. 2014;9(5):e96088
Authors: Moon EK, Park HJ, Oh CM, Jung KW, Shin HY, Park BK, Won YJ
BACKGROUND: In Korea, cancer is the third leading cause of death among adolescents and...
Comparison of secondary and primary thyroid cancer in adolescents and young adults.
Cancer. 2014 Apr 15;120(8):1155-1161
Authors: Goldfarb M, Freyer DR
BACKGROUND: Thyroid cancer is one of the 5 most common malignancies in adolescent and young adult (AYA) patients (ages...
Unmet information and support needs in newly diagnosed thyroid cancer: comparison of adolescents/young adults (AYA) and older patients.
J Cancer Surviv. 2014 Feb 26;
Authors: Goldfarb M, Casillas J
PURPOSE: Thyroid cancer (TC) is the most common cancer in...
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